|
KMID : 0364320010260030001
|
|
Journal of East-West Medicine
2001 Volume.26 No. 3 p.1 ~ p.24
|
|
|
Effect of Gamigyuibitang on the Penile Erection Induced by Apomorphine HCI and Erectic Dysfunction Induced by p,p-DDE
|
|
Byun Sung-Hee
|
|
|
Abstract
|
|
|
The effect of Gamigyuibitang on the penile erection induced by apomorphine HCl and on the erectile dysfunction induced by p,p-DDE, an environmental hormone derivate of DDT, were monitored using male cats. The changes of penile length, diameter & erectic periods were observed.
The results were as followed.
1. After induction of penile erection using apomorphine HCl, penile lengths in the Gamigyuinitang -dosing groups were significantly and dose-dependently increased compared to that of single dose of apomorphine HCl (ApG1 and ApG2) and p,p-DDE dosing group (DDEG).
2. After induction of penile erection using apomorphine HCl, penile diameters in the Gamigyuinitang-dosing groups were significantly and dose-dependently increased compared to that of single dose of apomorphine HC1 (ApG1 and ApG2) and p,p-DDE dosing group (DDEG).
3. After induction of penile erection using apomorphine HCl, erectic periods in the Gamigyuinitang-dosing groups were significantly and dose-dependently increased compared to that of single dose of apomorphine HCl (ApG1 and ApG2) and p,p-DDE dosing group (DDEG).
In conclusion, dose-dependent and significant increase of penile length, diameter & erectic periods were detected in the Gamigyuibitang-dosing groups compared to other groups.
According to these results, it is considered that Gamigyuibitang has some augmentation effect against to apomorphine HCl inducing penile erection and it also suggested that Gamigyuibitang has favorable effect to treatment of erectic dysfunctions induced by p,p-DDE.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|